# # A simple integrate-fire-burst model # # Author: # # Gregory D. Smith (757) 221-1989 office # Department of Applied Science (757) 221-2050 fax # The College of William and Mary # McGlothlin-Street Hall, Rm 305 greg@as.wm.edu # Williamsburg, VA 23187 http://www.as.wm.edu/Faculty/Smith.html # # Reference: # # Smith GD, Cox CL, Sherman SM, and Rinzel J. Fourier analysis of # sinusoidally-driven thalamocortical relay neurons and a minimal # integrate-and-fire-or-burst model. J. Neurophys., 83(1):588-610, 2000. # V(0)=-60 h(0)=0 p i0=-0.5,i1=1,freq=1,phi=0.0 p c=2, gh=0.07,thm=20,thp=100 p gl=0.035,Vl=-65,Vreset=-50,Vspike=-35, Vh=-60, Vt=120 global 1 V-Vspike {V=Vreset} i=i0+i1*cos(2*pi*t*freq/1000+phi) dV/dt=(i-gl*(V-Vl)-gh*heav(V-Vh)*h*(V-Vt))/c dh/dt=-h/thm*heav(V-Vh)-(h-1)/thp*heav(Vh-V) @ total=3000,trans=0,method=rungekutta,dt=0.01,axes=2,Xlo=0,Xhi=3000,Ylo=-150,Yhi=50,Yp=V,maxstore=10000000,bounds=100000 done